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Joint Health

Consumers are talking. Are you listening?

No longer just for the old, joint pain and discomfort are growing concerns among active individuals participating in a host of activities from CrossFit to running.

There is growing awareness that years of exercise could result in the accumulation of joint damage. 22% of the general US population indicated they are currently managing joint pain or stiffness1. Inflammation is a major contributor to the problems consumers are experiencing with their joints and is a top 10 key trend to pay attention to in 20182


Managing Joint Pain
Joint Supplement Market


A wide variety of joint health supplement ingredients exist

Consumers seeking joint health supplements in a market flourishing at $1.5b3 are sure to be bombarded with products containing a myriad of ingredients while shopping in store or online. While dozens of these ingredients have had relative success in the support of joint health, all are not created equal.

Let's look at some of the ingredients that are prominent in the joint supplement market:

Glucosamine - An important component of synovial fluid that lubricates your joints to prevent damage. It helps to generate new cartilage, helping to slow cartilage degeneration and repair connective tissue3.

Chondroitin - A primary structural component of joint cartilage which has been shown to beneficially support the treatment of osteoarthritis and joint inflammation3.

MSM (Methylsulfonylmethan) – Derived mostly from sulfur it has been a key player for supporting connective tissue and inflammation problems3

Silicon – The efficacy and safety of dietary silicon has been increasing and strongly supports its role in bone and connective tissue health3

Omega-3 fatty acids – Have been shown to support joint health.  Joints are sensitive to inflammation and Omega-3 fatty acids help to limit this inflammation3.

Calcium & Vitamin D – Essential for building strong and dense bones and joints. Vitamin D plays an important role in protecting bones and joints and the body requires it to absorb calcium3.

Boswellia serrata - Contains acetyl-11-keto-β-boswellic acid (AKBA) a potent inhibitor of 5-lipoxygenase, an enzyme responsible for inflammation and pain4.

Curcumin - A major component of turmeric and is considered to have potent antioxidant and anti-inflammatory properties.  The effect of curcumin likely originates through its ability to inhibit enzymes that mediate inflammatory processes (COX-2, LOX, iNOS)6.

Kaempferia galangal (Ginger extract) - Offers effective relief from chronic pain and in vivo studies suggest a functional anti-inflammatory effect7,8.

Piper nigrum oil (Black pepper) – Piperin is a key extract in black pepper that contains Beta Caryophyllene which bind to receptors that prevent the possible factor for inflammation9.

Consumers are seeking botanical and naturally sourced ingredients

The importance of “natural” cannot be denied as this trend can be found everywhere from supplements to food products. When it comes to choosing supplements for joint health, consumers are doing their research and choosing to forego non-steroidal anti-inflammatory drugs (NSAIDs) out of concern around possible side effects. Consumers are now more likely to consider botanically sourced ingredients because extracts like curcumin from turmeric, Boswellia serrata and ginger have been clinically substantiated to inhibit inflammation through various mechanisms, playing a key role in maintaining or supporting joint health. Considered even better by consumers are those products consisting of botanical ingredient combinations. The activity of individual ingredients through specific mechanisms as well as synergistic activity of all the ingredients for overall relief from joint discomfort is a preferred approach being taken by many3

The stats tell the story:

  • There has been a 29% increase in turmeric sales in the joint supplement category with a 2.4% decline in glucosamine & chondroitin for the fifth consecutive year3.  
Joint Supplement Category
  • Botanicals became the highest growing category in US supplements with a fourth consecutive year of sales growth over 7% at a total of 7.7% for 201610
  • All 5 of the top brands containing glucosamine & chondroitin have had reduced sales in the last year11

Acujoint™ is the solution your consumers are seeking

Acujoint is an advanced botanical joint health complex that is ideal for your tablet, capsule and gummy supplement applications. A composition of many of the popular botanical ingredients that your consumers are looking for and that are at the forefront of joint health, Acujoint contains:

  • Curcumin
  • Boswellia
  • Black pepper oil
  • Ginger extracts

Acujoint is backed by patent pending technology and scientifically supported. 

  • Its patent pending technology ensures that the botanical compounds are well protected, increasing bioavailability. 
  • In a clinical study, Acujoint was scientifically shown to support joint health by helping to support joint mobility and comfort12.
  • Acujoint was shown to reduce the VAS pain score and the WOMAC index score measuring pain, stiffness and physical function  (p-value= ≤ 0.001) in patients with knee osteoarthritis using 250mg of Acujoint as compared to glucosamine 1500 mg + chondroitin 1200 mg12
AcuJoint Graph

Acujoint’s superiority to the joint health staples, glucosamine and chondroitin are clear.


- Lower dose requirement:

  • Acujoint - 250mg/day
  • Glucosamine  - 1500/day
  • Chondroitin -  800-1200mg/day

- Acujoint includes innovative patent pending technology and the others do not.

- Naturally sourced:

  • Acujoint – a complex of 4 botanicals
  • Glucosamine – Sourced by processing chitin in shellfish
  • Chondroitin – Sourced through extracts of cartilage from animals 

Acujoint is a clean label ingredient. Consumers are becoming increasingly more interested in what their products contain. In addition to being naturally sourced, Acujoint provides you the ability to formulate your supplements to meet these clean label needs.

Acujoint Clean Label


At Glanbia Nutritionals, we constantly collaborate with new partners to keep our place at the forefront new ingredient development. Our industry-leading bioactives will help your products, and your consumers, perform at their best. Let us help you imagine what’s possible when you just add Glanbia.


1.    Natural Marketing Institute, Supplements, OTC, Rx Consumer Trends Report, 2016
2.    Natural Marketing Institute, 2016 Supplements/OTC/Rx Consumer Trends, pg 32)
3.    Nutrition Business Journal, Condition Specific Report, October 2017
4.    Z.M. Siddiqui. Indian J Pharm Sci. 2011 May-Jun; 73(3): 255–261.
5.    Bag A, Bhattacharyya SK, Chattopadhyay RR. The development of Terminalia chebula Retz. (Combretaceae) in clinical research. Asian Pac J Trop Biomed. 2013 Mar;3(3):244-52.
6.    Menon V.P., Sudheer A.R. (2007) antioxidant and anti-inflammatory properties of curcumin. In: aggarwal B.B., Surh YJ., Shishodia S. (Eds) the molecular targets and therapeutic uses of curcumin in health and disease. Advances in experimental medicine and biology, vol 595. Springer, boston, MA 
7.    Basri et al., Pharmacogn Rev. 2017 Jan-Jun; 11(21): 43–56. 
8.    Cao et al. Inflammation. 2014;37(5):1453–8. 
9.    Meghwal et al. Phytother Res. 2013 Aug;27(8):1121-30
10.    NutraIngredients, Data shows botanicals are the best-selling category of supplements, 17 Jul 2017 – from NBJ data
11.    New Nutrition Journal, 10 Key Trends in Food, Nutrition & Health 2018, Nov 2017
12.    Study not published. Data on file

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